Lipid 8-O14B, a novel bioreducible ionizable lipid, was developed to enhance the efficiency of protein delivery and genome editing. The presence of the disulfide bond in Lipid 8-O14B promotes endosomal escape and facilitates cargo release following lipid degradation within the reductive intracellular environment.
Anwendungsbeschreibung:
Categories: Ionizable Lipids, Lipids
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