Artikelnummer: EXB-A4-144-T100

Anti-Hu CD294 Alexa Fluor 488, Clone: [BM16], AF488, Monoclonal

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CD294 (prostaglandin D2 receptor 2) is a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells, but also on eosinophils and basophils. It mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3 UTR of CD294 gene have been associated with asthma susceptibility. Outside the immune system CD294 is expressed e.g. in gut, heart, and brain. The intracellular C terminal tail contains sites for phosphorylation by protein kinase C.

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Artikelname:	Anti-Hu CD294 Alexa Fluor 488, Clone: [BM16], AF488, Monoclonal
Artikelnummer:	EXB-A4-144-T100
Hersteller-Artikelnummer:	A4-144-T100
Alternativnummer:	EXB-A4-144-T100
Hersteller:	EXBIO
Kategorie:	Antikörper
Anwendung:	FC
Spezies-Reaktivität:	Human
Immunogen:	Human CD294 transfected rat cell line TART/B19-12.10
Konjugation:	AF488

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