Compound E, CAS [[209986-17-4]]

Artikelnummer: FBM-10-3479
Artikelname: Compound E, CAS [[209986-17-4]]
Artikelnummer: FBM-10-3479
Hersteller Artikelnummer: 10-3479
Alternativnummer: FBM-10-3479-1MG,FBM-10-3479-5MG
Hersteller: Focus Biomolecules
Kategorie: Biochemikalien
Alternative Synonym: Chemical Name: N-[(1S)-2-[[(3S)-2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluorobenzeneacetamide. Alternate Names: gamma-Secretase Inhibitor XXI, Cpd E
Gamma secretase inhibitor
Molekulargewicht: 490.51
Reinheit: 98% by TLC NMR (Conforms)
Formulierung: White solid
CAS Nummer: [209986-17-4]
Formel: C27H24F2N4O3
Anwendungsbeschreibung: Compound E (209986-17-4) is a potent and selective, cell permeable inhibitor of gamma-secretase which inhibits the cleavage of both amyloid precursor protein and Notch, IC50s ~ 3 nM.1,2 Inhibits growth and induces differentiation of neuroblastoma cells.3 Induces stem cell neuronal differentiation.4