RepSox, CAS [[446859-33-2]]

Produktübersicht

• Artikelname: RepSox, CAS [[446859-33-2]]
• Artikelnummer: FBM-10-4546
• Hersteller Artikelnummer: 10-4546
• Alternativnummer: FBM-10-4546-5MG,FBM-10-4546-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: E-616452, SNJ 2511, 616452

Produktbeschreibung

TGFbetaR-1 / ALK5 inhibitor

Produkteigenschaften

• Molekulargewicht: 287.32
• Reinheit: 99% by HPLC, NMR (Conforms)
• Formulierung: Pale yellow solid
• CAS Nummer: [446859-33-2]
• Formel: C17H13N5

Anwendungsbeschreibung

• Anwendungsbeschreibung: RepSox is a potent (IC50 ALK5 auto-P= 4 nM, IC50 TGF-b cellular assay = 23 nM) inhibitor of the TGF-beta type I receptor (ALK5).1 RepSox can replace Sox2 in reprogramming adult cells into pluripotent stem cells via induction of Nanog transcription.2 It was able to convert astrocytes into neuronal cells as part of a small molecule cocktail (along with valproic acid and CHIR99021).3,4