PD-L1 antibody, Unconjugated, Rabbit, Polyclonal

Produktübersicht

• Artikelname: PD-L1 antibody, Unconjugated, Rabbit, Polyclonal
• Artikelnummer: GTX104763
• Hersteller Artikelnummer: GTX104763
• Alternativnummer: GTX104763-100,GTX104763-25
• Hersteller: GeneTex
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: FC, ICC, IHC-Fr, IHC-P, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide encompassing a sequence within the Intracellular domain of human PD-L1. The exact sequence is proprietary.
• Konjugation: Unconjugated
• Alternative Synonym: CD274 molecule , B7-H , B7H1 , PD-L1 , PDCD1L1 , PDCD1LG1 , PDL1

Produktbeschreibung

PD-L1 antibody recognizes programmed death-ligand 1 (PD-L1) protein, also known as B7 homolog 1 (B7-H1) and cluster of differentiation 274 (CD274) protein. PD-L1 is found on various cancer cells and transduces immunosuppressive signals by binding to the programmed cell death protein 1 (PD-1) on effector T cells, thereby diminishing immune system attacks on malignant cells. Blocking the interaction between PD-L1 and PD-1 with PD-L1 antibodies is generating great clinical interest as a mode of immunotherapy against a number of cancers.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.97 mg/ml (Please refer to the vial label for the specific concentration.)
• Molekulargewicht: 33
• Sensitivitaet: This antibody is specific for human PDL1 protein, and it does not cross react with human PDL2 protein.,KO/KD validation is based on published data (PMID: 31905966 and 33608051).
• NCBI: 29126
• UniProt: Q9NZQ7
• Puffer: PBS, 20% Glycerol, 0.025% ProClin 300.
• Reinheit: Purified by antigen-affinity chromatography.
• Formulierung: Liquid

Anwendungsbeschreibung

• Anwendungsbeschreibung: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.