Mouse&Human Chimeric Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein, Ultra Low Endotoxin (ITG-HM1V6-UL)

Artikelnummer: KAB-ITG-HM1V6-UL
Artikelname: Mouse&Human Chimeric Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein, Ultra Low Endotoxin (ITG-HM1V6-UL)
Artikelnummer: KAB-ITG-HM1V6-UL
Hersteller Artikelnummer: ITG-HM1V6-UL
Alternativnummer: KAB-ITG-HM1V6-UL-100UG, KAB-ITG-HM1V6-UL-500UG
Hersteller: KactusBio
Kategorie: Proteine/Peptide
Spezies Reaktivität: Human, Mouse
Alternative Synonym: alphaVbeta6, Integrin alpha V beta 6, ITGAV&ITGB6,Integrin alpha V beta 6
Recombinant Mouse&Human Chimeric Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein is expressed from HEK293 with His tag at the C-terminus of ITGAV.It contains Phe31-Val988 (ITGAV) acidic tail and Gly22-Asn707 (ITGB6) basic tail.
Molekulargewicht: The protein has a predicted MW of 131.48 kDa (ITGAV) and 79.1 kDa (ITGB6). Due to glycosylation, the protein migrates to 120-160 kDa (ITGAV) and 90-120 kDa (ITGB6) based on Bis-Tris PAGE result.
Tag: C-His
UniProt: P43406
Puffer: Lyophilized from 0.22 µm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Expression System: HEK293
Reinheit: > 95% as determined by Bis-Tris PAGE,> 90% as determined by HPLC
Formulierung: Lyophilized
Sequenz: Phe31-Val988(ITGAV) acidic tail & Gly22-Asn707(ITGB6) basic tail
Target-Kategorie: Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer
The purity of Mouse&Human Chimeric ITGAV&ITGB6 is greater than 90% as determined by SEC-HPLC.
Mouse&Human Chimeric ITGAV&ITGB6 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Immobilized Human&Mouse Chimeric ITGAV&ITGB6, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human LAP (TGF beta 1), His Tag with the EC50 of 78.4ng/ml determined by ELISA.
Immobilized Mouse&Human Chimeric ITGAV&ITGB6, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-ITGB6 Antibody, hFc Tag with the EC50 of 4.8ng/ml determined by ELISA.
Immobilized Mouse&Human Chimeric ITGAV&ITGB6, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human Latent TGF beta 1, His-Avi Tag with the EC50 of 36.8ng/ml determined by ELISA.
Loaded Anti-ITGB6 Ab., hFc-Avi Tag on ProA-Biosensor can bind Human&Mouse Chimeric ITGAV&ITGB6, His Tag with an affinity constant of 76.20 nM as determined in BLI assay (Gator Prime).
Immobilized Mouse&Human Chimeric ITGAV&ITGB6, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-ITGAV&ITGB6 Antibody, hFc Tag with the EC50 of 3.7ng/ml determined by ELISA.