Sclerotiorin is a reversible and uncompetitive inhibitor against soybean lipoxygenase-1 (LOX-1) (IC50: 4.2 µM). Sclerotiorin also shows antioxidant activity by scavenging free radical (ED50: 0.12 µM), and nonenzymatic lipid peroxidation inhibition activity. Sclerotiorin has antifungal activity, and also inhibits platelet aggregation. Sclerotiorin can be purified from the fermented broth of Penicillium frequentans[1][2].
Molekulargewicht:
390.86
CAS Nummer:
[549-23-5]
Formel:
C21H23ClO5
Target-Kategorie:
Fungal,Lipoxygenase
Anwendungsbeschreibung:
Natural Products
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