Ammonium chloride, for molecular biology, CAS [[12125-02-9]] Preis auf Anfrage
Artikelnummer:
MCE-HY-Y1269D
Hersteller Artikelnummer:
HY-Y1269D
Alternativnummer:
MCE-HY-Y1269D-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Kits/Assays
Alternative Synonym:
Salmiac, for molecular biology
Ammonium chloride (Salmiac), for molecular biology is an inhibitor of Slc26a4 and SMAD2. Ammonium chloride, for molecular biology reduces the protein expression level of Slc26a4 in lung tissue, and attenuates ozone-induced increases in proinflammatory cytokines, inflammatory cells, pulmonary resistance, goblet cell hyperplasia, peribronchial inflammation and thiocyanate levels in mouse tissues and bronchoalveolar lavage fluid. Ammonium chloride, for molecular biology decreases the level of phosphorylated SMAD2, inhibits autophagy by reducing autophagy-related proteins, and enhances Cisplatin (HY-17394)-induced cancer cell apoptosis and DNA double-strand breaks. Ammonium chloride, for molecular biology also inhibits the TCA cycle, reduces ATP production, increases glucose utilization, regulates the levels of lactic acid, glutamic acid and ATP, and induces morphological degeneration of neuroblastoma cells. Ammonium chloride, for molecular biology can be used in studies related to ozone-induced airway injury, hepatocellular carcinoma, human cervical cancer, hepatic encephalopathy, Reye syndrome, epilepsy and neurodegenerative diseases[1][2][3][4].
Molekulargewicht:
53.49
CAS Nummer:
[12125-02-9]
Formel:
NH4Cl
Target-Kategorie:
Apoptosis,Chloride Channel,TGF-beta/Smad
Anwendungsbeschreibung:
MCE Product type: Biochemical Assay Reagents
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
