Produktbeschreibung
Total RNA was prepared from cell line WM989. WM989 is a melanoma cell line. This cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. This cell line expresses wild type N-RAS, c-KIT, and CDK4 genes. WM989 cells produce xenograft tumors when injected into immunocompromised mice.
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