| Has antibacterial properties. Jervine demonstrates teratogenic properties. It is the starting material for C-nor-D-homosteroids. Jervine induces holoprosencephaly and blocks endogenous Sonic hedgehog signaling. Melting Point: 248- 250C (decomposes) Solubility: Chloroform (sparingly), Dichloromethane Atmosphere: Air Method for Determining Identity: Proton NMR spectroscopic analysis TLC Conditions: SiO2, Dichloromethane: Methanol: Ammonium Hydroxide (90:10:1), Visualized with UV and AMCS, Single spot (Rf= 0.8). Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. |
