Transferrin is a single polypeptide chain glycoprotein and is a member of the iron binding family of proteins. It has a molecular weight of 79.5kD and a serum concentration range of 1800-2700mg/L. It is synthesized in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+. The iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in hemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. Applications: Suitable for use in Immunochemical reactions, as a control or standard in assays, conjugation, and most Immunological methods that requires highly purified proteins. Other applications not tested Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. For long-term storage, aliquot and store at -20C. Aliquots are stable for at least 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Certificate of Origin The raw animal product used in the manufacturing of Transferrin, Rat is derived from starting materials of North American origin. Collection was performed in USDA-inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation.
Reinheit:
Purified by ion exchange chromatography. IEP Assay shows a single precipitin arc against anti-rat Transferrin and anti-rat serum. Iron saturated (HOLO).
Formulierung:
Supplied as a liquid in PBS, pH 7.6. No preservative and no stabilizing proteins added.
CAS Nummer:
[11096-37-0]
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