GADD45B Antibody - middle region

Produktübersicht

• Artikelname: GADD45B Antibody - middle region
• Artikelnummer: ASB-ARP48346_P050
• Hersteller Artikelnummer: ARP48346_P050
• Alternativnummer: ASB-ARP48346_P050-25UL,ASB-ARP48346_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: IHC, WB
• Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GADD45B
• Alternative Synonym: MYD118, GADD45BETA

Produktbeschreibung

The function of GADD45B is involved in the regulation of growth and apoptosis.This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 18kDa
• NCBI: 4616
• UniProt: O75293
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Bilder

Sample Type: Human Prostate Cancer
Primary Antibody Dilution: 2ug/mL
Color/Signal Descriptions: GADD45B (DAB, brown), nuclei (hematoxylin, blue)
Gene Name: GADD45B

Sample Type: Human Prostate Cancer
Primary Antibody Dilution: 2ug/mL
Color/Signal Descriptions: GADD45B (DAB, brown), nuclei (hematoxylin, blue)
Gene Name: GADD45B

Sample Type: Human Prostate Cancer
Primary Antibody Dilution: 2ug/mL
Color/Signal Descriptions: GADD45B (DAB, brown), nuclei (hematoxylin, blue)
Gene Name: GADD45B

WB Suggested Anti-GADD45B Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysate

Host: Mouse
Target Name: GADD45B
Sample Tissue: Mouse Small Intestine
Antibody Dilution: 1ug/ml

Host: Rabbit
Target Name: GA45B
Sample Type: Fetal Lung lysates
Antibody Dilution: 3.0ug/ml

Host: Rabbit
Target Name: GADD45B
Sample Tissue: Human Lung Tumor
Antibody Dilution: 1ug/ml

Host: Rabbit
Target Name: GADD45B
Sample Tissue: Human Jurkat Whole Cell
Antibody Dilution: 1ug/ml

GADD45B antibody - middle region (ARP48346_P050) in Human HepG2 using Western Blot