SGCE Antibody - N-terminal region

Product Overview

• Article Name: SGCE Antibody - N-terminal region
• Biozol Catalog Number: ASB-ARP46387_P050
• Supplier Catalog Number: ARP46387_P050
• Alternative Catalog Number: ASB-ARP46387_P050-25UL,ASB-ARP46387_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SGCE
• Alternative Names: ESG, DYT11, epsilon-SG

Product Description

SGCE is a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with myoclonus-dystonia syndrome. Alternative splicing results in multiple transcript variants.The SGCE gene encodes the epsilon member of the sarcoglycan family, transmembrane components of the dystrophin-glycoprotein complex, which links the cytoskeleton to the extracellular matrix.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 50 kDa
• NCBI: 8910
• UniProt: B5MDA7
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Immunohistochemistry with pFA fixed human skeletal muscle tissue at an antibody concentration of 5.0ug/ml using anti-SGCE antibody (ARP46387_P050)

Immunohistochemistry with cerebellum tissue

WB Suggested Anti-SGCE Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: 721_B cell lysateSGCE is supported by BioGPS gene expression data to be expressed in 721_B

Host: Rabbit
Target Name: WT1
Sample Type: 721_B
Antibody Dilution: 1.0ug/mlSGCE is supported by BioGPS gene expression data to be expressed in 721_B

Host: Rabbit
Target Name: FAM46C
Sample Type: Human Fetal Liver
Antibody Dilution: 1.0ug/ml

Host: Rabbit
Target Name: CHAD
Sample Type: Human Adult Placenta
Antibody Dilution: 1.0ug/ml

Host: Rabbit
Target: SGCE
Positive control (+): Human Fetal Heart (HE)
Negative control (-): Human Brain (BR)
Antibody concentration: 1ug/ml

25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment.

SGCE antibody - N-terminal region (ARP46387_P050) in Human 721_B using Western Blot