Ketoconazole (base), CAS [[65277-42-1]]

Produktübersicht

• Artikelname: Ketoconazole (base), CAS [[65277-42-1]]
• Artikelnummer: FBM-10-1015
• Hersteller Artikelnummer: 10-1015
• Alternativnummer: FBM-10-1015-100MG,FBM-10-1015-500MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: ()-1-[4-(4-{[-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]ethan-1-one

Produktbeschreibung

Cytochrome P450 inhibitor

Produkteigenschaften

• Molekulargewicht: 531.43
• Reinheit: >98% by TLC
• Formulierung: Off-white solid
• CAS Nummer: [65277-42-1]
• Formel: C26H28Cl2N4O4

Anwendungsbeschreibung

• Anwendungsbeschreibung: Ketoconazole is a broad spectrum antifungal agent which acts via inhibition of a cytochrome P450, CYP51A1 which is a lanosterol 14-demethylase.1 Also inhibits CYP3A and CYP1A1.2 Inhibits adrenal steroidogenesis.3 Downregulates cholesterol synthesis in drug-tolerant human lung cancer cell lines.4 Blocks the biosynthesis of leukotrienes (LT) via inhibition of 5-lipoxygenase and dose dependently inhibits LT-mediated bronchoconstriction in guinea pigs.5

Bilder

10-1015