DBCO-PEG2-Val-Cit-PAB-MMAE is an ADC linker featuring a DBCO group, a Val-Cit dipeptide, a PAB motif, and an MMAE warhead. The DBCO group is a click chemistry handle which readily reacts with azide groups, while the Val-Cit is a protease-cleavable dipeptide which releases the MMAE warhead into cells via an elimination mechanism.
Molekulargewicht:
1569.92
Reinheit:
99.27
CAS Nummer:
[2845934-59-8]
Formel:
C84H120N12O17
Target-Kategorie:
ADC Linker
Anwendungsbeschreibung:
MCE Product type: ADC Related
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