GS-6201 (CVT-6883) is a selective adenosine A2B receptor antagonist. GS-6201 displays high affinity and selectivity for the human adenosine A2B receptors (Ki=22 nM)[1]. GS-6201 reduces caspase-1 activity in the heart, and attenuates cardiac remodeling after acute myocardial infarction (AMI) in the mouse[2]. GS-62013 attenuates the airway reactivity induced by NECA, AMP, or allergen in sensitized mice[3].
Molekulargewicht:
446.43
Reinheit:
99.72
CAS Nummer:
[752222-83-6]
Formel:
C21H21F3N6O2
Target-Kategorie:
Adenosine Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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