mPEG-amine (MW 750), CAS [[80506-64-5]] Preis auf Anfrage
Artikelnummer:
MCE-HY-155882
Hersteller Artikelnummer:
HY-155882
Alternativnummer:
MCE-HY-155882-100MG,MCE-HY-155882-50MG
Hersteller:
MedchemExpress
Kategorie:
Kits/Assays
Alternative Synonym:
mPEG-NH2 (MW 750)
mPEG-amine (mPEG-NH2) (MW 750) is a chemical modification reagent for nanoparticles, capable of covalently binding to Ad-PVA to form Ad-PVA-PEG polymers. mPEG-amine (mPEG-NH2) (MW 750) stabilizes gene delivery complexes by providing steric hindrance, reducing particle aggregation, while enhancing the water solubility and serum stability of the complex, reducing carrier cytotoxicity, and assisting in the efficient condensation of pDNA by cationic components to form nanoparticles that can be endocytosed by cells. mPEG-amine (MW 750) can also be used to synthesize folate-conjugated polymer micelles for encapsulating the anticancer agent Camptothecin (HY-16560). Folate-conjugated polymer micelles are effective carriers for poorly soluble anticancer drugs, capable of avoiding macrophages and acting through folate receptor (FR)-mediated endocytosis to target tumor cells. mPEG-amine (mPEG-NH2) (MW 750) can be applied to research in the field of non-viral gene delivery, as a component of gene delivery vectors, facilitating the safe and efficient delivery of nucleic acid drugs to target cells[1][2].
Molekulargewicht:
750(Average)
Reinheit:
90
CAS Nummer:
[80506-64-5]
Formel:
(C2H4O)nC3H9NO
Target-Kategorie:
Biochemical Assay Reagents
Anwendungsbeschreibung:
MCE Product type: Biochemical Assay Reagents
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