3D Bio-Tissues
Bio-equivalent tissues
3D Bio-Tissues (3DBT) is at the forefront of producing bio-equivalent tissues for clinical and cellular agriculture markets. 3DBT is focused on the development of the next generation of cutting-edge biotech solutions aimed at radically transforming the delivery of sustainable solutions.
Product Highlight: CityMix
City-Mix is a patented, non-toxic culture media supplement that acts as an effective “cell booster”.
It's composed of a specific formulation of inert, food safe, high molecular weight molecules that facilitate macromolecular crowding.
Macromolecular crowding creates pockets of higher concentration of soluble media components such as growth factors in solution. This in turn improves enzyme kinetics and provides cells with a biophysical & biochemical environment similar to in vivo.
By mimicking the in vivo environment we see several important changes in cell behaviour, namely:
- Cellular proliferation rates increase, significantly increasing yield.
- Less supplements are required, reducing the need for expensive growth factors and recombinant proteins, e.g. 4% v/v City Mix typically reduces the recombinant cytokine and albumin requirement by 50-75% without inhibiting proliferation, greatly reducing the cost of serum free media.
- Facilitates tissues production via extracellular matrix establishment.
- Completely eliminates the need for serum (BSA & FBS) without inhibiting cell growth.
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