Antibody Production Service Develop your own monoclonal or polyclonal antibody

Antibodies, or immunoglobulins, are produced by B lymphocytes during the adaptive immune response. Following secretion, they bind with an extremely high degree of specificity to the foreign antigen which stimulated their production. This functions to protect the host from harm by, for example, marking invading pathogens for destruction or preventing viruses from attaching to host cell receptors. Their highly specialised binding makes antibodies a hugely powerful research tool, and they have been used for decades in a wide variety of immunodetection te...

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Recombinante Protein Expression Service Recombinant Proteins designed according to your wishes

Recombinant proteins are proteins that are artificially made through the recombinant DNA technology. Proteins can be used in many areas, such as diagnostic tools, vaccines, therapeutics, detergents, cosmetics, food production, and feed additives. Isolating proteins from their natural sources cannot meet the growing demand on proteins in research and industry. Furthermore, in many cases the recombinant protein must meet certain requirements like a specific Tag, high purity and amount and sequence modifications. At BIOZOL you have the opportun...

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Antibody and Protein Conjugation Service Conjugate your antibody or protein with a wide range of different tags

Antibody and protein conjugation, also known as antibody and protein labeling, describes the modification of antibodies or proteins by the attachment of specific tags.  like enzymes, fluorescent proteins, fluorescent dyes, biotin and strepatividin and different particles. These tags allow directly or indirectly the specific detection of the conjugated antibody or protein and in the case of conjugated antibodies the specific detection of the antigen. Due to this new property, labeled proteins can be used e.g. in localization studies, for compound...

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ELISA and Assay Development Services Develop your own ELISA or Assay perfectly tailored to your needs

ELISA (enzyme-linked immunosorbent assay) is a plate-based assay technique designed for detecting and quantifying peptides, proteins, antibodies and hormones. In an ELISA, an antigen must be immobilized to a solid surface and then complexed with an antibody that is linked to an enzyme. Detection is accomplished by assessing the conjugated enzyme activity via incubation with a substrate to produce a measureable product. The most crucial element of the detection strategy is a highly specific antibody-antigen interaction. ELISAs are typically p...

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Vector Design Service Design your vector with the awards winning VectorBuilder tool

In molecular biology, the term cloning describes the introduction of deoxyribonucleic acids (DNA) into circular DNA molecules, so-called vectors. Cloning is one of the standard methods of molecular biology. With its help, DNA sequences can be amplified for subsequent use in downstream applications. The free and web-based design tool of our partner Vectorbuilder provides you a highly intuitive workflow to design your desired vector with just a few mouse clicks. Additional services can be easily added, e.g. customized cloning an...

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Hybridoma Sequencing Service Give immortality to your antibody

Hybridoma cell lines are the result of a fusion of a B lymphocyte with a myeloma or thymoma cell. Hybridoma cells thus combine the properties of lymphocytes with the immortality of tumour cells. However, the tumour cell used must not express any antibodies. The B-cell hybridoma cell line resulting from the fusion is suitable as a classical source of monoclonal antibodies with defined specificity. Due to their immortality they are now able to produce monoclonal antibodies in large quantities. Hybridoma sequencing involves the sequencing of...

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Antibody Protein Sequencing Service No hybridoma cell line? No problem!

Sometimes it is not possible to sequence the hybridoma cell line because it has been lost or is unavailable for some other reason. If a sufficient amount of the monoclonal antibody is still present, the protein can also be sequenced directly. In contrast to DNA or RNA, which only consist of four different building blocks, proteins have a more complex structure. They consist of at least 20 different amino acids, which can also be chemically modified. The sequencing of proteins is therefore more difficult than with nucleic acids....

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Polyclonal Antibody Sequencing Service Create your reproducible, polyclonal reagent

In cooperation with our partners you have the possibility to use a polyclonal antibody sequencing service at BIOZOL. With this service you have the possibility to create a reproducible, polyclonal reagent of defined content or to use the native immune system to identify new antibody candidates. Polyclonal antibodies are antibodies that are directed against the same antigen but against different epitopes. Any natural infection or immunization leads to a polyclonal immune response by multiple clones of B-lymphocytes. The polyclonal reagent des...

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