GenuIN Biotechnologies

Knockdown-validated antibodies

At GenuIN Biotechnologies, a proprietary ShGE™ gene silencing platform enables the performance of high-throughput and low-cost antibody validation. GenuIN's platform is built on a uniquely optimized biotechnology that sets the company apart — no other solution matches its performance or design.

The platform is based on lentivirus-mediated delivery of short hairpin RNAs (shRNAs) to silence gene expression and reduce corresponding protein levels. This generates a reliable negative control for assessing antibody specificity. An antibody is considered specific if it produces a detectable signal in positive control cells, but that signal is absent or significantly diminished in gene-silenced cells.

GenuIN's goal is to increase the offered number of shRNA knockdown (KD)-validated antibodies. Along the way, their gene silencing platform gives us lentivirus, cell line, and cell lysate libraries that we can use to provide additional, high quality products and services.

 

Product Range:

• KD-Validated Monoclonal Antibodies 
• KD-Validated Lentiviral Particles
• KD-Validated Cell Lysates
• Monoclonal Antibodies
• IVD Antibodies
• Flow Cytometry Antibodies
• Tag and Loading Control Antibodies
• Secondary Antibodies
• IntactProtein Cell-Tissue Lysis Kit
• Other Reagents

https://www.genuinbiotech.com/

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