MF-DH-300 is a 15-PGDH inhibitor with an IC50 of 1.6 nM. It blocks the interaction between 15-PGDH and PGE2, promoting stem cell proliferation, increasing muscle strength, and enhancing mitochondrial function. Additionally, MF-DH-300 raises the expression of survival motor neuron (SMN) protein and is applicable in research on muscle diseases such as spinal muscular atrophy (SMA).
Molekulargewicht:
330.38
CAS Nummer:
[2673403-86-4]
Formel:
C20H18N4O
Target-Kategorie:
Dehydrogenase
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