DBCO-PEG4-Desthiobiotin can be incorporated to biomolecules via strain-promoted Alkyne-Azide Chemistry (SPAAC) which does not need a Cu (I) catalysis or heating. Desthiobiotin binds less tightly to streptavidin than biotin and therefore Desthiobiotin labelled biomolecules can easily be eluted from streptavidin affinity resin by using free biotin. The introduction of the hydrophilic PEG4-moity reduces aggregation and precipitation during the labeling reaction by increasing the hydrophilicity.
Molecular Weight:
719.87 g/mol
Purity:
95% (HPLC)
Form:
Oil
CAS Number:
[2032788-37-5]
Formula:
C39H53N5O8
Application Notes:
Fluorescent labeling via click chemistry
DBCO-PEG4-Desthiobiotin
DBCO-PEG4-Desthiobiotin
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