Catalog Number: BOT-BNC400238-100

PLAP (Placental Alkaline Phosphatase)(ALPP/238), CF640R conjugate, 0.1mg/mL, Clone: [ALPP/238], Mouse, Monoclonal

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PLAP is a tissue specific, trophoblast-derived, 70 kDa, glycosyl-phosphatidylinositol (GPI)-anchored, dimeric, Zn2 metallo glycoprotein that catalyzes the hydrolysis of phosphomonoesters into an inorganic phosphate and an alcohol. It is present in the placenta and serum of pregnant women and in high frequency in gynecological and testicular cancers and in lower frequency in other tumors. The three tissue-specific APs in humans, PLAP, germ cell AP (GCAP) and intestinal AP, are 90-98% homologous. Non-tissue specific AP is found in kidney, liver and bone. This MAb binds equally well to all common allelic variants (S, F, FS and I) of PLAP as to AP from normal human testis. This MAb can be used both as coating as well as tracer antibody in the same ELISA to detect PLAP in serum of S, F, FS and I phenotypes.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

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Article Name:	PLAP (Placental Alkaline Phosphatase)(ALPP/238), CF640R conjugate, 0.1mg/mL, Clone: [ALPP/238], Mouse, Monoclonal
BIOZOL Catalog Number:	BOT-BNC400238-100
Supplier Catalog Number:	BNC400238-100
Alternative Catalog Number:	BOT-BNC400238-100-100UL
Manufacturer:	Biotium
Host:	Mouse
Category:	Antikörper
Species Reactivity:	Human
Immunogen:	Recombinant full-length human ALPP protein
Conjugation:	CF640R
Alternative Names:	Alkaline phosphatase placental type\|Alkaline phosphatase Regan Isozyme\|ALP\|Alp1\|ALPP\|Germ-cell alkaline phosphatase\|nagao Isozyme\|PALP\|Placental alkaline phosphatase 1\|placental heat-stable alkaline phosphatase\|PLAP-1\|PLAP1

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