Catalog Number: BOT-BNC941342-500

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1342), CF594 conjugate, 0.1mg/mL, Clone: [CFTR/1342], Mouse, Monoclonal

Images (0)

Product Description

This antibody recognizes a protein of 165-170 kDa, identified as cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3,5-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

* VAT and shipping costs not included. Errors and price changes excepted

Availability10 Tage

Product Guarantee and Expert Support

Article Name:	CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1342), CF594 conjugate, 0.1mg/mL, Clone: [CFTR/1342], Mouse, Monoclonal
BIOZOL Catalog Number:	BOT-BNC941342-500
Supplier Catalog Number:	BNC941342-500
Alternative Catalog Number:	BOT-BNC941342-500-500UL
Manufacturer:	Biotium
Host:	Mouse
Category:	Antikörper
Application:	IHC
Species Reactivity:	Human, Mouse
Immunogen:	Recombinant human full-length CFTR
Conjugation:	CF594
Alternative Names:	ABC35, ATP Binding Cassette Superfamily C Member 7 (ABCC7), cAMP-dependent chloride channel, CFTR, CFTR/MRP, Channel conductance-controlling ATPase, Cystic Fibrosis Transmembrane Conductance Regulator, MRP7, TNR CFTR

Product Overview

Product Properties

Application Notes

Images