InVivoMAb anti-mouse CD4, Clone: [GK1.5], Rat, Monoclonal
Catalog Number:
BXC-BE0003-1-INDUSTRIAL
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| Article Name: | InVivoMAb anti-mouse CD4, Clone: [GK1.5], Rat, Monoclonal |
| Biozol Catalog Number: | BXC-BE0003-1-INDUSTRIAL |
| Supplier Catalog Number: | BE0003-1 |
| Alternative Catalog Number: | BXC-BE0003-1-1MG,BXC-BE0003-1-5MG,BXC-BE0003-1-25MG,BXC-BE0003-1-50MG,BXC-BE0003-1-100MG |
| Manufacturer: | Bio X Cell |
| Host: | Rat |
| Category: | Antikörper |
| Species Reactivity: | Mouse |
| Immunogen: | Mouse CTL clone V4 |
| The GK1.5 monoclonal antibody reacts with the mouse CD4. The CD4 antigen is a 55 kDa cell surface type I membrane glycoprotein belonging to the immunoglobulin superfamily. CD4 acts as a co-receptor which in cooperation with the T cell receptor (TCR) interacts with class II MHC molecules displayed by antigen presenting cells (APC). CD4 is expressed by the majority of thymocytes, most helper T cells, a subset of NK-T cells and weakly by dendritic cells and macrophages. CD4 plays an important role in the development of T cells and is required for mature T cells to function optimally. The GK1.5 antibody has been shown to compete with clones YTS 177 and YTS 191 for CD4 binding. |
| Clonality: | Monoclonal |
| Concentration: | Lot specific,typically between 4-11 mg/ml |
| Clone Designation: | [GK1.5] |
| Molecular Weight: | 150 kDa |
| Pubmed: | 27775706 |
| Buffer: | PBS, pH 6.5, Contains no stabilizers or preservatives |
| Purity: | 95% , Determined by SDS-PAGE |
| Form: | Liquid |
| Formula: | PBS, pH 6.5, Contains no stabilizers or preservatives |
| Target: | CD4 |
| Application Notes: | in vivo CD4+ T cell depletion, Flow cytometry, Western blot |
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