InVivoMAb anti-mouse CD8alpha, Clone: [53-6.7], Rat, Monoclonal
Catalog Number:
BXC-BE0004-1-INDUSTRIAL
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| Article Name: | InVivoMAb anti-mouse CD8alpha, Clone: [53-6.7], Rat, Monoclonal |
| Biozol Catalog Number: | BXC-BE0004-1-INDUSTRIAL |
| Supplier Catalog Number: | BE0004-1 |
| Alternative Catalog Number: | BXC-BE0004-1-1MG,BXC-BE0004-1-5MG,BXC-BE0004-1-25MG,BXC-BE0004-1-50MG,BXC-BE0004-1-100MG |
| Manufacturer: | Bio X Cell |
| Host: | Rat |
| Category: | Antikörper |
| Species Reactivity: | Mouse |
| Immunogen: | Mouse Spleen Cells or Thymocyte Membranes |
| The 53-6.7 monoclonal antibody reacts with mouse CD8alpha. The CD8 antigen is a transmembrane glycoprotein that acts as a co-receptor for the T cell receptor (TCR). Like the TCR, CD8 binds to class I MHC molecules displayed by antigen presenting cells (APC). CD8 is primarily expressed on the surface of cytotoxic T cells, but can also be found on thymocytes, natural killer cells, and some dendritic cell subsets. CD8 most commonly exists as a heterodimer composed of one CD8alpha and one CD8beta chain however, it can also exist as a homodimer composed of two CD8alpha chains. Both the CD8alpha and CD8beta chains share significant homology to immunoglobulin variable light chains. The molecular weight of each CD8 chain is approximately 34 kDa. The 53-6.7 antibody exhibits depleting activity when used in vivo. |
| Clonality: | Monoclonal |
| Concentration: | Lot specific,typically between 4-11 mg/ml |
| Clone Designation: | [53-6.7] |
| Molecular Weight: | 150 kDa |
| Pubmed: | 24446520 |
| Buffer: | PBS, pH 6.5, Contains no stabilizers or preservatives |
| Purity: | 95% , Determined by SDS-PAGE |
| Form: | Liquid |
| Formula: | PBS, pH 6.5, Contains no stabilizers or preservatives |
| Target: | CD8alpha |
| Application Notes: | in vivo CD8+ T cell depletion, Immunofluorescence, Flow cytometry, Western blot |
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