InVivoMAb anti-mouse Ly6G/Ly6C (Gr-1), Clone: [RB6-8C5], Rat, Monoclonal

Product Overview

• Article Name: InVivoMAb anti-mouse Ly6G/Ly6C (Gr-1), Clone: [RB6-8C5], Rat, Monoclonal
• Biozol Catalog Number: BXC-BE0075-INDUSTRIAL
• Supplier Catalog Number: BE0075
• Alternative Catalog Number: BXC-BE0075-1MG,BXC-BE0075-5MG,BXC-BE0075-25MG,BXC-BE0075-50MG,BXC-BE0075-100MG
• Manufacturer: Bio X Cell
• Host: Rat
• Category: Antikörper
• Species Reactivity: Mouse
• Immunogen: Mouse granulocytes

Product Description

The RB6-8C5 monoclonal antibody reacts strongly with mouse Ly6G and weakly with mouse Ly6C previously referred to as GR-1. Ly6G is a 21-25 kDa member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Ly6G is expressed differentially during development by cells in the myeloid lineage including monocytes macrophages granulocytes and neutrophils. Monocytes typically express Ly6G transiently during development while mature granulocytes and peripheral neutrophils retain expression making Ly6G a good cell surface marker for these populations.The RB6-8C5 antibody has been shown to inhibit the binding of the 1A8 antibody. The 1A8 monoclonal antibody reacts specifically with mouse Ly6G with no reported cross reactivity with Ly6C.

Product Properties

• Clonality: Monoclonal
• Concentration: Lot specific,typically between 4-11 mg/ml
• Clone Designation: [RB6-8C5]
• Molecular Weight: 150 kDa
• Pubmed: 25043618
• Buffer: PBS, pH 7.0, Contains no stabilizers or preservatives
• Purity: 95% , Determined by SDS-PAGE
• Form: Liquid
• Formula: PBS, pH 7.0, Contains no stabilizers or preservatives
• Target: Ly6G/Ly6C

Application Notes

• Application Notes: in vivo depletion of Gr-1+ myeloid cells, Flow cytometry, Immunohistochemistry (paraffin), Immunohistochemistry (frozen)

Images

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