Catalog Number: BXC-BE0112

InVivoMAb anti-mouse PD-L2 (B7-DC), Clone: [TY25], Rat, Monoclonal

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The TY25 monoclonal antibody reacts with mouse PD-L2 (programmed death ligand 2) also known as B7-DC or CD273. PD-L2 is a 25 kDa type I transmembrane protein that belongs to the B7 family of the Ig superfamily. PD-L2 is expressed on monocytes, macrophages and subsets of dendritic cells. PD-L2 binds to its receptor, PD-1, found on CD4 and CD8 thymocytes as well as activated T and B lymphocytes and myeloid cells. Engagement of PD-L2 with PD-1 leads to inhibition of TCR-mediated T cell proliferation and cytokine production. The TY25 antibody has been reported to block PD-1 mediated interactions in vivo.

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Article Name:	InVivoMAb anti-mouse PD-L2 (B7-DC), Clone: [TY25], Rat, Monoclonal
BIOZOL Catalog Number:	BXC-BE0112
Supplier Catalog Number:	BE0112
Alternative Catalog Number:	BXC-BE0112-1MG,BXC-BE0112-5MG,BXC-BE0112-25MG,BXC-BE0112-50MG,BXC-BE0112-100MG
Manufacturer:	Bio X Cell
Host:	Rat
Category:	Antikörper
Species Reactivity:	Mouse
Immunogen:	Mouse PD-L2 transfected cell line

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