Catalog Number: BXC-BE0153

InVivoMAb anti-mouse BTLA (CD272), Clone: [PK18.6], Rat, Monoclonal

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Product Description

The PK18.6 monoclonal antibody reacts with mouse B- and T-lymphocyte attenuator (BTLA) also known as CD272. BTLA is an Ig superfamily member which is expressed on B cells, T cells, macrophages, dendritic cells, NK cells, and NKT cells. Like PD-1 and CTLA-4, BTLA interacts with a B7 homolog, B7-H4. However, unlike PD-1 and CTLA-4, BTLA displays T cell inhibition via interaction with tumor necrosis family receptors, not just the B7 family of cell surface receptors. BTLA is a ligand for herpes virus entry mediator (HVEM). BTLA-HVEM complexes have been shown to negatively regulate T cell immune responses.

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Article Name:	InVivoMAb anti-mouse BTLA (CD272), Clone: [PK18.6], Rat, Monoclonal
BIOZOL Catalog Number:	BXC-BE0153
Supplier Catalog Number:	BE0153
Alternative Catalog Number:	BXC-BE0153-1MG,BXC-BE0153-5MG,BXC-BE0153-25MG,BXC-BE0153-50MG,BXC-BE0153-100MG
Manufacturer:	Bio X Cell
Host:	Rat
Category:	Antikörper
Species Reactivity:	Mouse
Immunogen:	Mouse BTLA external domain-human IgG fusion protein

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