Catalog Number: BXC-BE0210-INDUSTRIAL

InVivoMAb anti-mouse BTLA (CD272), Clone: [8F4], Mouse, Monoclonal

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Product Description

The 8F4 monoclonal antibody reacts with mouse B- and T-lymphocyte attenuator (BTLA) also known as CD272. BTLA is an Ig superfamily member which is expressed on B cells, T cells, macrophages, dendritic cells, NK cells, and NKT cells. Like PD-1 and CTLA-4, BTLA interacts with a B7 homolog, B7-H4. However, unlike PD-1 and CTLA-4, BTLA displays T cell inhibition via interaction with tumor necrosis family receptors, not just the B7 family of cell surface receptors. BTLA is a ligand for herpes virus entry mediator (HVEM). BTLA-HVEM complexes have been shown to negatively regulate T cell immune responses. The 8F4 antibody reacts with BALb/c and C57BL/6 mouse BLTA.

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Article Name:	InVivoMAb anti-mouse BTLA (CD272), Clone: [8F4], Mouse, Monoclonal
BIOZOL Catalog Number:	BXC-BE0210-INDUSTRIAL
Supplier Catalog Number:	BE0210
Alternative Catalog Number:	BXC-BE0210-1MG,BXC-BE0210-5MG,BXC-BE0210-25MG,BXC-BE0210-50MG,BXC-BE0210-100MG
Manufacturer:	Bio X Cell
Host:	Mouse
Category:	Antikörper
Species Reactivity:	Mouse
Immunogen:	C57BL/6 mouse BTLA Ig domain

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