Catalog Number: BXC-BE0310-INDUSTRIAL

InVivoMAb anti-mouse VISTA, Clone: [13F3], Hamster, Monoclonal

Images (5)

Product Description

The 13F3 monoclonal antibody reacts with mouse V-domain Ig suppressor of T cell activation (VISTA) also known as PD-1H and B7-H5. VISTA is a 309 aa type I transmembrane glycoprotein and a member of the Ig superfamily. VISTA is expressed on naive and activated T cells, NK cells, macrophages, dendritic cells, and neutrophils. VISTA functions as a negative immune-checkpoint protein that suppresses T cell cytokine production and proliferation. VISTA is overexpressed by tumor-infiltrating lymphocytes, such as myeloid cells and regulatory T cells. Blockade of VISTA with the 13F3 antibody results in delayed tumor growth in mouse models of melanoma.

* VAT and shipping costs not included. Errors and price changes excepted

Availability3 Tage

Product Guarantee and Expert Support

Article Name:	InVivoMAb anti-mouse VISTA, Clone: [13F3], Hamster, Monoclonal
BIOZOL Catalog Number:	BXC-BE0310-INDUSTRIAL
Supplier Catalog Number:	BE0310
Alternative Catalog Number:	BXC-BE0310-1MG,BXC-BE0310-5MG,BXC-BE0310-25MG,BXC-BE0310-50MG,BXC-BE0310-100MG
Manufacturer:	Bio X Cell
Host:	Hamster
Category:	Antikörper
Species Reactivity:	Mouse
Immunogen:	EL4 cells overexpressing mouse VISTA-RFP and then boosted with VISTA-Ig fusion protein

Product Overview

Product Properties

Application Notes

Images