Product Description
The 30H12 monoclonal antibody reacts with mouse Thy1.2 also known as CD90.2. Thy1.2 is expressed by thymocytes and mature T lymphocytes as well as hematopoietic stem cells, neurons, epithelial cells, and fibroblasts. Thy1.2 is expressed only by certain mouse strains including C57BL/6, BALB/c, CBA, C3H, C58/, SJL, DBA, and NZB/. Thy1.2 is a 25-35 kDa GPI-anchored membrane glycoprotein and a member of the immunoglobulin superfamily. The function of Thy1.2 has not been fully elucidated but is thought to play roles in cognition, axon growth, T lymphocyte function, and apoptosis. The 30H12 monoclonal antibody has been reported to induce Ca2+ flux in thymocytes. This antibody is particularly useful for depletion of T lymphocytes.
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