Compound 401 is a cell-permeable pyrimido-isoquinolinone compound that acts as a potent, reversible, and ATP-competitive inhibitor of DNA-PK (IC50 = 280 nM) with ~19-fold selectivity over FRAP (mTOR) (IC50 = 5.3 µM).
Molecular Weight:
281.3092
CAS Number:
[168425-64-7]
Formula:
C16H15N3O2
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