Bcl-2 Mouse mAb, IgG1, Monoclonal

Product Overview

• Article Name: Bcl-2 Mouse mAb, IgG1, Monoclonal
• Biozol Catalog Number: EBT-EM1041
• Supplier Catalog Number: EM1041
• Alternative Catalog Number: EBT-EM1041-50, EBT-EM1041-100
• Manufacturer: ELK Biotechnology
• Host: Mouse
• Category: Antikörper
• Application: IF, IHC, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic Peptide
• Alternative Names: B-Cell Leukemia/Lymphoma 2 ,B-Cell CLL/Lymphoma 2

Product Description

BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell death by controlling the mitochondrial membrane permeability.

Product Properties

• Clonality: Monoclonal
• Concentration: 1mg/mL
• Molecular Weight: 26kDa
• Isotype: IgG1
• NCBI: 596
• UniProt: P10415

Application Notes

• Application Dilute: WB 1:1,000-2,000 IHC 1:200 IF 1:100-200

Images

Western blot analysis of Hela with Bcl-2 mouse mAb(6B5) diluted at 1:1,000.

IHC staining of Human tonsil tissue paraffin-embedded with Bcl-2 mouse mAb(6B5)diluted at 1:200.

Western blot analysis of 3T3 with Bcl-2 mouse mAb(6B5) diluted at 1:1,000.

IF analysis of Hela with EM1041(Left) and DAPI (Right) diluted at 1:100.