Pioglitazone HCl, CAS [[112529-15-4]]

Product Overview

• Article Name: Pioglitazone HCl, CAS [[112529-15-4]]
• Biozol Catalog Number: FBM-10-1010
• Supplier Catalog Number: 10-1010
• Alternative Catalog Number: FBM-10-1010-20MG, FBM-10-1010-100MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione hydrochloride

Product Description

PPARgamma agonist

Product Properties

• Molecular Weight: 392.090
• Purity: 98% by TLC, NMR (conforms)
• Form: White solid
• CAS Number: [112529-15-4]
• Formula: C19H20N2O3S HCl

Application Notes

• Application Notes: Pioglitazone is a clinically useful antidiabetic drug.1 It is a selective agonist of the human peroxisome proliferator-activated receptor 1(PPAR, EC50 = 490 nM2, 550nM3) with weak agonist activity at PPAR and no activity at PPAR.2 Inhibits mitochondrial pyruvate metabolism and glucose production in hepatocytes.4 Suppresses production of inflammatory cytokines and shows antidepressant-like activity in mouse models.5