Chemical Name: 5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione maleate. Alternate Names: Avandia, BRL49653
PPARgamma agonist
Molecular Weight:
357.43
Purity:
98% by TLC, NMR (Conforms)
Form:
White solid
CAS Number:
[155141-29-0]
Formula:
C18H19N3O3S
Application Notes:
Prototypical TZD antidiabetic agent. Potent and selective PPARgamma agonist (Kd=43 nM).1,2 Clinically useful antihyperglycemc agent.3 Induces a brown fat gene program in subcutaneous white adipose tissue via activation of the PRDM16 protein.4 Induces differentiation of pluripotent stem cells into adipocytes.5
* VAT and and shipping costs not included. Errors and price changes excepted