Chemical Name: 2-[4-(Trifluoromethyl)phenyl]-7,8-dihydro-5H-thiino[4,3-d]pyrimidin-4-ol
Tankyrase inhibitor, Cardiomyogenesis inducer
Molecular Weight:
312.31
Purity:
98% by TLC, NMR Conforms
Form:
White or off-white solid
CAS Number:
[284028-89-3]
Formula:
C14H11F3N2OS
Application Notes:
Tankyrase inhibitor (IC50=11 and 4 nM for TNKS1 and 2 respectively). Antagonizes wnt signaling via stimulation of ß-catenin degradation and stabilization of actin.1 Robustly induces cardiomyogenesis of stem cells.2 Cell Permeable
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