Compound E, CAS [[209986-17-4]]

Product Overview

• Article Name: Compound E, CAS [[209986-17-4]]
• Biozol Catalog Number: FBM-10-3479
• Supplier Catalog Number: 10-3479
• Alternative Catalog Number: FBM-10-3479-1MG,FBM-10-3479-5MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: N-[(1S)-2-[[(3S)-2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluorobenzeneacetamide. Alternate Names: gamma-Secretase Inhibitor XXI, Cpd E

Product Description

Gamma secretase inhibitor

Product Properties

• Molecular Weight: 490.51
• Purity: 98% by TLC NMR (Conforms)
• Form: White solid
• CAS Number: [209986-17-4]
• Formula: C27H24F2N4O3

Application Notes

• Application Notes: Compound E (209986-17-4) is a potent and selective, cell permeable inhibitor of gamma-secretase which inhibits the cleavage of both amyloid precursor protein and Notch, IC50s ~ 3 nM.1,2 Inhibits growth and induces differentiation of neuroblastoma cells.3 Induces stem cell neuronal differentiation.4