Verteporfin, CAS [[129497-78-5]]

Product Overview

• Article Name: Verteporfin, CAS [[129497-78-5]]
• Biozol Catalog Number: FBM-10-3487
• Supplier Catalog Number: 10-3487
• Alternative Catalog Number: FBM-10-3487-5MG, FBM-10-3487-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: (4R,4aS)-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-benzo[b]porphine-9,13-dipropanoic acid monomethyl ester. Alternate Names: CL 318,952, BPD-MA

Product Description

YAP inhibitor

Product Properties

• Molecular Weight: 718.79
• Purity: 98% by TLC NMR (Conforms)
• Form: Black solid
• CAS Number: [129497-78-5]
• Formula: C41H42N4O8

Application Notes

• Application Notes: Verteporfin inhibits transcription by YAP/TAZ, IC50 = 2.5 µM, (via disruption of YAP-TEAD interaction) inhibiting autophagy and halting proliferation of cancer and cancer stem cell lines.1,2 Inhibits autophagosome formation.3 Reverses differentiation of Src-overexpressing embryonic stem cells.4 May be used to ablate unwanted neovasculature in the eye, esophageal mucosa, and elsewhere using light to create damaging free radicals.5