Emricasan, CAS [[254750-02-2]]

Product Overview

• Article Name: Emricasan, CAS [[254750-02-2]]
• Biozol Catalog Number: FBM-10-4280
• Supplier Catalog Number: 10-4280
• Alternative Catalog Number: FBM-10-4280-5MG,FBM-10-4280-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: IDN-6556, PF-03491390

Product Description

pan-Caspase inhibitor

Product Properties

• Molecular Weight: 569.51
• Purity: 98% by HPLC, NMR (Confirms)
• Form: White solid
• CAS Number: [254750-02-2]
• Formula: C26H27F4N3O7

Application Notes

• Application Notes: Emricasan is a liver-targeted antiapoptotic pan-caspase inhibitor.1,2 It has been investigated as a hepatoprotective agent in the treatment of liver ischemia3 and NASH/NAFLD liver injury4,5. Emricasan protected SNB-19 cells against cell death induced by Zika virus strains MR766, FSS13025, and PRVABC59.6 Emricasan improves the viability of hPSCs and their differentiated progeny when used in a small molecule cocktail (CEPT) containing chroman 1, polyamines and trans-ISRIB.7