TM-25659, CAS [[260553-97-7]]

Product Overview

• Article Name: TM-25659, CAS [[260553-97-7]]
• Biozol Catalog Number: FBM-10-4293
• Supplier Catalog Number: 10-4293
• Alternative Catalog Number: FBM-10-4293-5MG, FBM-10-4293-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 2-Butyl-5-methyl-6-pyridin-3-yl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazo[4,5-b]pyridine

Product Description

TAZ activator

Product Properties

• Molecular Weight: 500.61
• Purity: 98% by HPLC NMR (Conforms)
• Form: Off-white solid
• CAS Number: [260553-97-7]
• Formula: C30H28N8

Application Notes

• Application Notes: TM-25659 is a TAZ activator that significantly increases TAZ nuclear localization. It suppressed PPARgamma-dependent adipogenesis and enhanced osteoblast differentiation in vitro and in vivo.1 TM-25659 decreased insulin resistance and inflammation in mice via activation of GCN2 pathways.2 It promoted osteogenic differentiation in both adipose-derived stem cells3 and mesenchymal stem cells4.