IWR-1 endo, CAS [[1127442-82-3]]

Product Overview

• Article Name: IWR-1 endo, CAS [[1127442-82-3]]
• Biozol Catalog Number: FBM-10-5081
• Supplier Catalog Number: 10-5081
• Alternative Catalog Number: FBM-10-5081-5MG, FBM-10-5081-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 4-(1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl)-N-8-quinolinyl-benzamide

Product Description

Wnt signaling inhibitor

Product Properties

• Molecular Weight: 409.44
• Purity: 98% by TLC/HPLC NMR (Conforms)
• Form: Off white or yellow solid
• CAS Number: [1127442-82-3]
• Formula: C25H19N3O2

Application Notes

• Application Notes: A potent inhibitor of Wnt signaling (IC50=180 nM).1 Inhibits zebrafish tailfin regeneration (0.5 mM).2 Acts via inhibition of tankyrase and attenuates Wnt/b-catenin signaling in cancer stem-like cells.3 Promotes self-renewal and maintains pluripotency of human embryonic stem cells.4 Promotes differentiation of pluripotent stem cells into cardiomyocytes.5