Human/Cynomolgus Activin RIIA/ACVR2A Protein, Ultra Low Endotoxin (ARA-HM22A-UL)

Product Overview

• Article Name: Human/Cynomolgus Activin RIIA/ACVR2A Protein, Ultra Low Endotoxin (ARA-HM22A-UL)
• Biozol Catalog Number: KAB-ARA-HM22A-UL
• Supplier Catalog Number: ARA-HM22A-UL
• Alternative Catalog Number: KAB-ARA-HM22A-UL-100UG, KAB-ARA-HM22A-UL-500UG
• Manufacturer: KactusBio
• Category: Proteine/Peptide
• Species Reactivity: Human, Monkey
• Alternative Names: ACTR-IIA, ACTRIIA, ACVR2A, ACVR2

Product Description

Recombinant Human/Cynomolgus Activin RIIA/ACVR2A Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Ala20-Pro135.

Product Properties

• Molecular Weight: The protein has a predicted MW of W 39.35 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result.
• Tag: C-hFc (IgG1)
• UniProt: P27037
• Buffer: Lyophilized from 0.22 µm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
• Expression System: HEK293
• Purity: > 95% as determined by Bis-Tris PAGE,> 95% as determined by HPLC
• Form: Lyophilized
• Sequence: Ala20-Pro135
• Target: Activin RIIA/ACVR2A

Images

The purity of Human/Cynomolgus Activin RIIA is greater than 95% as determined by SEC-HPLC.

Human/Cynomolgus Activin RIIA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Immobilized Human Activin A, No Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human/Cynomolgus Activin RIIA, hFc Tag with the EC50 of 1.6ng/ml determined by ELISA (QC Test).

Immobilized Human/Mouse/Rat GDF-8, No Tag at 2 ug/ml (100 ul/well) on the plate. Dose response curve for Human/Cynomolgus Activin RIIA, hFc Tag with the EC50 of 56.9ng/ml determined by ELISA.

Human Activin RIIA, hFc Tag captured on CM5 Chip via Protein A can bind Human/Mouse/Rat GDF-8, No Tag with an affinity constant of 0.13 nM as determined in SPR assay (Biacore T200).