Cynomolgus/Rhesus macaque BCMA/TNFRSF17 Protein (BCM-CM117)

Product Overview

• Article Name: Cynomolgus/Rhesus macaque BCMA/TNFRSF17 Protein (BCM-CM117)
• Biozol Catalog Number: KAB-BCM-CM117
• Supplier Catalog Number: BCM-CM117
• Alternative Catalog Number: KAB-BCM-CM117-100UG, KAB-BCM-CM117-500UG
• Manufacturer: KactusBio
• Category: Proteine/Peptide
• Species Reactivity: Monkey
• Alternative Names: CD269, TNFRSF17, BCMA, BCM, TNFRSF13A

Product Description

Recombinant Cynomolgus/Rhesus macaque BCMA/TNFRSF17 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Ala53.

Product Properties

• Molecular Weight: The protein has a predicted MW of 7.10 kDa. Due to glycosylation, the protein migrates to 13-23 kDa based on Bis-Tris PAGE result.
• Tag: C-His
• UniProt: A0A2K5UD97
• Buffer: Lyophilized from 0.22 µm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
• Expression System: HEK293
• Purity: > 95% as determined by Bis-Tris PAGE,> 95% as determined by HPLC
• Form: Lyophilized
• Sequence: Met1-Ala53
• Target: BCMA/TNFRSF17

Images

Cynomolgus/Rhesus macaque BCMA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Cynomolgus/Rhesus macaque BCMA is greater than 95% as determined by SEC-HPLC.

Immobilized Cynomolgus BCMA, His Tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-BCMA Antibody, hFc Tag with the EC50 of 3.2 ng/ml determined by ELISA.

Immobilized Cynomolgus BCMA, His Tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for Biotinylated Human APRIL (Trimer), His Tag with the EC50 of 15.8 ng/ml determined by ELISA (QC Test).

Biotinylated Cynomolgus BAFF (Trimer), His Tag captured on CM5 Chip via streptavidin can bind Cynomolgus BCMA, His Tag with an affinity constant of 1.40 µM as determined in SPR assay (Biacore T200).

Loaded Anti-BCMA antibody on ProA-Biosensor can bind Cynomolgus BCMA, His Tag with an affinity constant of 8.99 nM as determined in BLI assay (Gator Prime).

Loaded Biotinylated Cynomolgus BAFF (Trimer), His-Avi-Flag Tag on Streptavidin-Biosensor, can bind Cynomolgus BCMA, His Tag with an affinity constant of 1.69 µM as determined in BLI assay (Gator).

Loaded Biotinylated Human APRIL (Trimer), His-Avi Tag on Streptavidin-Biosensor can bind Cynomolgus BCMA, His Tag with an affinity constant of 5.75 nM as determined in BLI assay (Gator Prime).