Biotinylated Human CD20/MS4A1 VLP (CD2-HM123B)

Catalog Number: KAB-CD2-HM123B
Article Name: Biotinylated Human CD20/MS4A1 VLP (CD2-HM123B)
Biozol Catalog Number: KAB-CD2-HM123B
Supplier Catalog Number: CD2-HM123B
Alternative Catalog Number: KAB-CD2-HM123B-100UG
Manufacturer: KactusBio
Category: Sonstiges
Species Reactivity: Human
Conjugation: Biotin
Alternative Names: MS4A1, CD20, MS4A-1, B1, Bp35, CD20 receptor, CD20S7, CVID5, LEU-16, Ly-44, MS4A2, S7
Recombinant Biotinylated Human CD20/MS4A1 VLP is expressed from HEK293.It contains Met1-Pro297 (It may have cross reaction with anti-His antibody).
Molecular Weight: The target protein has a predicted MW of 34.3 kDa.
UniProt: P11836
Buffer: Supplied as 0.22µm filtered solution in PBS, 300mM L-arginine (pH 7.4).
Expression System: HEK293
Purity: > 95% as determined by HPLC
Form: Liquid
Sequence: Met1-Pro297
Target: CD20/MS4A1
The purity of Biotinylated Human CD20 VLP is greater than 95% as determined by SEC-HPLC.
Biotinylated Human CD20 VLP captured on CM5 Chip via streptavidin can bind Ofatumumab, hFc Tag with an affinity constant of 0.22 nM as determined in SPR assay (Biacore T200).
Biotinylated Human CD20 VLP captured on CM5 Chip via streptavidin can bind Rituximab, hFc Tag with an affinity constant of 0.40 nM as determined in SPR assay (Biacore T200).
Immobilized Biotinylated Human CD20 VLP at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Rituximab, hFc Tag with the EC50 of 14.7ng/ml determined by ELISA (QC Test).
Immobilized Biotinylated Human CD20 VLP at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Ofatumumab, hFc Tag with the EC50 of 13.9ng/ml determined by ELISA.
Immobilized Biotinylated Human CD20 VLP at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Obinutuzumab, hFc Tag with the EC50 of 3.6ng/ml determined by ELISA.