Human IL-22R alpha 1 Protein (ILR-HM222)

Product Overview

• Article Name: Human IL-22R alpha 1 Protein (ILR-HM222)
• Biozol Catalog Number: KAB-ILR-HM222
• Supplier Catalog Number: ILR-HM222
• Alternative Catalog Number: KAB-ILR-HM222-100UG, KAB-ILR-HM222-500UG
• Manufacturer: KactusBio
• Category: Proteine/Peptide
• Species Reactivity: Human
• Alternative Names: IL-22R-alpha-1, IL-22RA1, CRF2-9, IL22R, IL22R1, IL-TIF-R1, zcytoR11

Product Description

Recombinant Human IL-22R alpha 1 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus, It contains His16-Thr228.

Product Properties

• Molecular Weight: The protein has a predicted MW of 51 kDa. Due to glycosylation, the protein migrates to 60-68 kDa based on Bis-Tris PAGE result.
• Tag: C-hFc (IgG1)
• UniProt: Q8N6P7
• Buffer: Lyophilized from 0.22 µm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
• Expression System: HEK293
• Purity: > 95% as determined by Bis-Tris PAGE,> 95% as determined by HPLC
• Form: Lyophilized
• Sequence: His16-Thr228
• Target: IL-22R alpha 1

Images

Human IL-22R alpha 1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Immobilized Human IL-22R alpha 1, hFc Tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for Biotinylated Anti-IL-22R alpha 1 Antibody, hFc Tag with the EC50 of 19.2 ng/ml determined by ELISA.

Immobilized Human IL-22, His Tag at 2 ug/ml (100 ul/Well) on the plate. Dose response curve for Human IL-22R alpha 1, hFc Tag with the EC50 of 10.6 ng/ml determined by ELISA (QC Test).

The purity of Human IL-22R alpha 1 is greater than 95% as determined by SEC-HPLC.

Loaded Human IL-22R alpha 1, hFc Tag on ProA-Biosensor can bind Human IL-22, His Tag with an affinity constant of 42.60 nM as determined in BLI assay (Gator Prime).

Loaded Biotinylated Anti-IL-22RA1 Antibody, hFc-Avi Tag on Streptavidin-Biosensor can bind Human IL-22RA1, hFc Tag with an affinity constant of 1.14 nM as determined in BLI assay (Gator Prime).