Quipazine, a 5-HT (serotonin) agonist, demonstrates affinity for the 5-HT3R receptor in rats with a Ki value of 1.4 nM, effectively displacing GR65630. It exhibits antiviral activity against SARS-CoV-2, achieving an EC50 of 31.64 µM. Additionally, Quipazine acts as a 5-HT3R agonist in peripheral models, indicating its potential for neurological disease research.
Molecular Weight:
213.28
CAS Number:
[4774-24-7]
Formula:
C13H15N3
Target:
SARS-CoV|||Others|||5-HT Receptor
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