Product Description
L-Iduronic acid is an epimer of glucuronic acid and a monosaccharide component of glycosaminoglycans (GAGs), including heparin and chondroitin sulfate B, found on the outer cell membrane.1 L-Iduronic acid is conformationally flexible, which allows it to bind metal ions and may be important for the antithrombotic activity of heparin.2,3 Iduronic acid-containing GAGs are selectively bound by basic fibroblast growth factor (bFGF), which prevents infection of Hep-2 cells with respiratory syncytial virus (RSV) in vitro.1 Synonyms: L-IdoA, L-Idopyranosid, L-Iduronate, Sodium L-Iduronate, L-Iduronic Acid Monosodium Salt CAS No: 61199-83-5 Free acid: 2073-35-0 Molecular Formula: C6H9NaO7 Molecular Weight: 216.12 Appearance: Beige to brown powder Purity: 95% Melting Point: 90C (dec.) Solubility: Methanol (Slightly, Heated), Water (Slightly) Method for Determining Identity: 1H NMR (D20) and Mass Spectrometric Analysis TLC Conditions: C18, Isopropanol: Ethyl Acetate: Water: Ammonium Hydroxide=4:4:2:1, Visualized with AMCS and KMnO4, spingle spot, Rf=0.40 Atmosphere: Inert Gas Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C for 6 months after receipt Hygroscopic, Under Inert Atmosphere. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
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