Molecular Formula: C20H22N4O5 . CH3SO3H Molecular Weight: 494.5 Camostat is a trypsin-like protease inhibitor known to inhibit trypsin and various inflammatory proteases including plasmin, kallikrein, and thrombin. A special diet containing 1 mg/g camostat has been shown to inhibit the production of TNF-alpha and monocyte chemoattractant protein-1 by monocytes and to disrupt proliferation of pancreatic stellate cells in a rat model of pancreatic fibrosis.Protease regulation via camostat has also been reported to reversibly inhibit epithelial sodium channel function in human airway epithelial cell models (IC50 = 50 nM) and to enhance mucociliary clearance for up to five hours when administered by aerosol inhalation to sheep.
Reinheit:
>=98%
Application Verdünnung:
A stock solution may be made by dissolving the camostat (mesylate) in the solvent of choice. Camostat (mesylate) is soluble in organic solvents such as DMSO and dimethyl formamide, which should be purged with an inert gas. The solubility of camostat (mesy
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