Eperezolid, CAS [[165800-04-4]]

Artikelnummer: MCE-HY-10393
Artikelname: Eperezolid, CAS [[165800-04-4]]
Artikelnummer: MCE-HY-10393
Hersteller Artikelnummer: HY-10393
Alternativnummer: MCE-HY-10393-100MG,MCE-HY-10393-10MG,MCE-HY-10393-10MMX1ML,MCE-HY-10393-5MG,MCE-HY-10393-50MG,MCE-HY-10393-25MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Alternative Synonym: PNU-100592
Eperezolid (PNU-100592) is an orally active protein synthesis inhibitor that targets the bacterial 50S ribosomal subunit. Eperezolid competitively binds to a specific site on the ribosomal 50S subunit (overlapping with the binding sites of chloramphenicol (HY-B0239) and lincomycin (HY-117660)) to inhibit the translation initiation stage and exert antibacterial activity. Eperezolid can induce host cell autophagy to enhance the clearance of intracellular mycobacteria, and its MIC90 for Staphylococcus aureus and Enterococcus is 1-4 µg/mL. Eperezolid is mainly used for antibacterial research on infections with Gram-positive bacteria such as methicillin-resistant (HY-121544) Staphylococci and vancomycin-resistant (HY-B0671) Enterococci, as well as infections with intracellular bacteria such as Mycobacterium tuberculosis[1][2][3][4].
Molekulargewicht: 394.40
Reinheit: 96.55
CAS Nummer: [165800-04-4]
Formel: C18H23FN4O5
Target-Kategorie: Antibiotic,Bacterial
Anwendungsbeschreibung: MCE Product type: Reference compound1